Viagra Information
Viagra, is a brand name well-known for the drug Sildenafil citrate. It is also sold under the name Ravatio and Cavertia in few places across the world. It is developed, produced and marketed by the pharmaceutical company Pfizer. The prime competitors of Pfizer in the market are tadalafil (Cialis) and Vardenafil (Levitra). The main purpose for the production of this drug is to treat male erectile dysfunction (ED or impotence) and pulmonary arterial hypertension (PAH). Viagra is obtained in three different dosages; 25mg, 50mg, and 100mg. This drug is comes through doctor’s prescription. But these days it is gained on internet also as it is widespread.
Initially Viagra was not intended to treat ED. In the late 1990s it was formed to cure a form of heart disease called angina pectoris. As it did not work that purpose and showed few signs of consistent erections. It was then that the drug was patented in 1996 and approved for the treatment of ED. ED is a common complaint in men, which occurs due to several factors. Many of the causes can be due to psychological reasons whereas few causes can be due to physiological disorders. It is found that every 1 in 10 men suffer with ED at some point in their lives. In few cases of ED, which is caused by the damage to the nervous system, diabetes or hypogonadism, and these cases Viagra may not be effective.
Viagra is ranked as a phosphodiesterase type5 (PDE5) inhibitor. Basically PDE5 results in a compound called cyclic guanosine monophosphate or cGMP to lower. As the cGMP causes the arterial smooth muscles in the penis to relax, which then allows the penis becomes congest with blood which is how an erection is generated. A few other drugs which perform on the same procedures are Tadalafil and Vardenafil. Sildenafil is metabolized by hepatic enzymes and excreted by both the liver and kidneys.
As mentioned earlier, Viagra is found to be sold in three different dosages of 25mg, 50mg and 100mg. All three costing US$10 per pill. Usually it is recommended to start the medication with 50mg pill and then the dosage is lowered or raised accordingly which is appropriate. And the dosage for the pulmonary arterial hypertension which is cured by the drug Revatio is a 20mg pill three times a day. The Viagra pills are blue and diamond shaped pills with the words ‘Pfizer’ engraved on one side and ‘VGR xx’ engraved on the other side of it. Xx stands for the dosage of the pill such as 25 or 50 or 100. Viagra certainly has few side effects. Few of the common side effects are sneezing, headache, stomach upset, flushing and sweating. The list also includes dyspepsia (indigestion), palpitations (irregular, rapid pulsation of the heart) and photophobia (abnormal fear of light). In few cases there are reports of blurred vision and in very rare cases temporary blindness is found. Cautions should be taken by the patients who also consume Protease inhibitors for the treatment of HIV as this increases the severity of side effects. Thus patients taking protease inhibitors are recommended to limit their dosage of sildenafil no more than 25mg pill every 48 hours.
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